Hypothyroid Myopathy (HYPOTM)

15:40 Posted by Ahmed Khalil

Definition
a disease in which underproduction of thyroxine, which is normally produced by the thyroid gland, causes muscle damage
 
Cause
often an autoimmune disease, a mistaken attack by the immune system, in this case on the thyroid gland
 
Onset
childhood to adulthood
 
Symptoms
weakness around hips and sometimes shoulders; slowing of reflexes; possible muscle stiffness and cramps; can cause muscle enlargement along with weakness; can cause rhabdomyolysis, a severe breakdown of muscle tissue
 
Progression
can usually be almost completely alleviated by restoring normal thyroxine levels through medication
 
Inheritance
There appears to be a genetic predisposition to autoimmune diseases.
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